StructureDefinition-tmb

Sourcehl7.fhir.uv.genomics-reporting#current:Genomics Reporting Implementation Guide (v4.0.1)
resourceTypeStructureDefinition
idtmb
canonicalhttp://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/tmb
version2.1.0-SNAPSHOT
statusactive
publisherHL7 Clinical Genomics Working Group
nameTMB
titleTumor Mutation Burden
date2023-07-25T14:43:25+00:00
descriptionThe total number of mutations (changes) found in the DNA of cancer cells. Knowing the tumor mutational burden may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. Tumor mutational burden is being used as a type of biomarker.
copyrightThis material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.
jurisdictionsuv
fhirVersion4.0.1
kindresource
abstractfalse
sdTtypeObservation
derivationconstraint
basehttp://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-base
Usages(none)
Name Flags Card. Type Description & Constraints doco
. . Observation GenomicsBase Tumor Mutation Burden
. . . code 94076-7
Required Pattern: At least the following
. . . . coding 1..* Coding Code defined by a terminology system
Fixed Value: (complex)
. . . . . system 1..1 uri Identity of the terminology system
Fixed Value: http://loinc.org
. . . . . code 1..1 code Symbol in syntax defined by the system
Fixed Value: 94076-7
. . . Slices for value[x] Slice: Unordered, Open by type:$this
. . . . value[x]:valueQuantity 0..1 Quantity Required Pattern: At least the following
. . . . . system 1..1 uri System that defines coded unit form
Fixed Value: http://unitsofmeasure.org
. . . . . code 1..1 code Coded form of the unit
Fixed Value: 1/1000000{Base}
. . . . . unit Required Pattern: Mutations/Megabase
. . . interpretation Binding: High Low codes ( required )

doco Documentation for this format

Produced 08 Sep 2023