| Name | Flags | Card. | Type |
Description & Constraints
|
|---|---|---|---|---|
Observation
|
Observation | |||
Slices for extension
|
Slice: Unordered, Open by value:url | |||
spanning-pairs
|
S | 0..1 | integer |
Number of reads pairs spanning the fusion URL: https://build.fhir.org/ig/arkhn/arkhn-ig-osiris/StructureDefinition/spanning-pairs |
value[x]
|
||||
|
split-reads
|
S | 0..1 | integer |
Number of reads containing the fusion point URL: https://build.fhir.org/ig/arkhn/arkhn-ig-osiris/StructureDefinition/split-reads |
|
value[x]
|
||||
|
code
|
Type of the fusion event. eg: translocation, readthrough Binding: Fusion Type Value Set ( required ) |
|||
subject
|
Reference (Oncology Patient) | |||
Slices for derivedFrom
|
1 .. | Slice: Unordered, Open by pattern:reference | ||
derivedFrom:fusion-molecular-sequences
|
0..2 | Reference (5 Prime Molecular Sequence | 3 Prime Molecular Sequence) | Five prime and three prime positions of the fusion | |
derivedFrom:analysis
|
1..1 | Reference (Sequencing Analysis) | Analysis from which come this observation | |
Slices for component
|
1 .. | Slice: Unordered, Open by pattern:code | ||
component:actionability
|
0..1 | Conclusion of the clinicians wether the variant is actionable or not during the Molecular Tumor Board | ||
code
|
Required Pattern: At least the following | |||
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://loinc.org |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: 93348-1 |
|
value[x]
|
boolean | |||
|
component:proposed-for-orientation
|
0..1 | Is the ClinicalTumorBoardConclusion used to orient the treatment decision ? | ||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://terminology.hl7.org/CodeSystem/umls |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: C0449889 |
|
|
value[x]
|
boolean | |||
|
component:pathogenicity
|
0..1 | Conclusion of the biologist on the pathogenicity of the variant before the Molecular Tumor Board | ||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://loinc.org |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: 74019-1 |
|
value[x]
|
CodeableConcept | Binding: Pathogenicity Value Set ( required ) | ||
|
component:gene-studied
|
0..* |
Gene studied [ID] |
||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://loinc.org |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: 48018-6 |
|
|
value[x]
|
1.. | CodeableConcept |
If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used. Binding: todo ( extensible ) |
|
|
component:in-frame
|
1..1 | Specify whether the fusion is in frame | ||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://loinc.org |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: 95123-6 |
|
|
value[x]
|
boolean | |||
|
Documentation for this format
|
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