| Name | Flags | Card. | Type |
Description & Constraints
|
|---|---|---|---|---|
Observation
|
Variant | |||
subject
|
Reference (Oncology Patient) | |||
Slices for derivedFrom
|
1 .. | Slice: Unordered, Open by pattern:reference | ||
derivedFrom:Analysis
|
1..1 | Reference (Sequencing Analysis) | Analysis from which come this observation | |
|
component:cytogenetic-location
|
||||
|
component:ref-sequence-assembly
|
||||
value[x]
|
||||
|
component:variation-code
|
||||
|
value[x]
|
||||
|
component:copy-number
|
||||
|
value[x]
|
||||
|
component:exact-start-end
|
||||
|
value[x]
|
||||
|
low
|
||||
|
high
|
||||
|
component:variant-length
|
||||
|
component:actionability
|
0..1 | Conclusion of the clinicians wether the variant is actionable or not during the Molecular Tumor Board | ||
code
|
Required Pattern: At least the following | |||
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://loinc.org |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: 93348-1 |
|
value[x]
|
boolean | |||
|
component:proposed-for-orientation
|
0..1 | Is the ClinicalTumorBoardConclusion used to orient the treatment decision ? | ||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://terminology.hl7.org/CodeSystem/umls |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: C0449889 |
|
|
value[x]
|
boolean | |||
|
component:pathogenicity
|
0..1 | Conclusion of the biologist on the pathogenicity of the variant before the Molecular Tumor Board | ||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://loinc.org |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: 74019-1 |
|
value[x]
|
CodeableConcept | Binding: Pathogenicity Value Set ( required ) | ||
|
component:loss-of-heterozygosity
|
0..1 | Is the segment located in a region of loss of heterozygosity ? (can be independant from copy number information | ||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://terminology.hl7.org/CodeSystem/umls |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: C1881449 |
|
|
value[x]
|
boolean | |||
component:segment-intensity
|
0..1 | Intensity of the measured signal | ||
|
code
|
Required Pattern: At least the following | |||
|
coding
|
1..* | Coding |
Code defined by a terminology system Fixed Value: (complex) |
|
|
system
|
1..1 | uri |
Identity of the terminology system Fixed Value: http://terminology.hl7.org/CodeSystem/umls |
|
|
code
|
1..1 | code |
Symbol in syntax defined by the system Fixed Value: C2732930 |
|
|
value[x]
|
integer | |||
|
Documentation for this format
|
||||