| # | | Name | Source | Ver | Description |
| 1 | | ADHA Core Substance | au.digitalhealth.r4#current | R4 | The purpose of this profile is to provide a core representation of a substance for the electronic exchange of health information between individuals, healthcare providers, and the My Health Record system infrastructure in Australia. |
| 2 | | AU Base Substance | hl7.fhir.au.base#current | R4 | This profile defines a substance structure that localises core concepts, including terminology, for use in an Australian context. The purpose of this profile is to provide national level agreement on core localised concepts. This profile does not force conformance to core localised concepts. It enables implementers and modellers to make their own rules, i.e. [profiling](http://hl7.org/fhir/profiling.html), about how to support these concepts for specific implementation needs. |
| 3 | | AU Core Substance | hl7.fhir.au.core#current | R4 | This profile sets minimum expectations for a Substance resource to record, search, and fetch substances associated with a patient. It is based on the [AU Base Substance](http://build.fhir.org/ig/hl7au/au-fhir-base/StructureDefinition-au-substance.html) profile and identifies the *additional* mandatory core elements, extensions, vocabularies and value sets that **SHALL** be present in the Substance when conforming to this profile. It provides the floor for standards development for specific uses cases in an Australian context.
In AU Core a Substance resource is used within the context of a referencing resource. |
| 4 | | BC Substance Profile | hl7.fhir.us.breastcancer#0.2.0 | R3 | Any matter of defined composition that has discrete existence, whose origin may be biological, mineral or chemical. |
| 5 | | CRMI SubstanceDefinition | hl7.fhir.uv.crmi#current | R4 | Represents the definition of a substance, suitable for use in various contexts |
| 6 | | Drug Substance Manufactured Batch | hl7.fhir.us.pq-cmc#current | R5 | Includes the properties of the drug substance as manufactured. |
| 7 | | HCIM LaboratoryTestResult Substance | nictiz.fhir.nl.stu3.zib2017#2.2.15 | R3 | The Substance details from the LaboratoryTestResult.specimen.microorganism as defined by the Dutch Health and Care Information models (Dutch: Zorginformatiebouwsteen or ZIB) version 4.1, release 2017. |
| 8 | | no-basis-Substance | hl7.fhir.no.basis#2.1.2 | R4 | Basis profile for Substances to be used in Norway. The profile is adapted to use FEST as source of information. |
| 9 | | QICore Substance | hl7.fhir.us.qicore#current | R4 | Profile of Substance for decision support/quality metrics. Defines the core set of elements and extensions for quality rule and measure authors. |
| 10 | | Specimen Additive Substance XpanDH | hl7.eu.fhir.xpandh.lab#current | R4 | Specimen Additive Substance XpanDH |
| 11 | | Substance (specimen additive) - Lab Report | hl7.fhir.it.lab-report#current | R4 | Descrive la risorsa Substance additiva del campione nel dominio del Lab Report. |
| 12 | | Substance - dx-PQ | hl7.fhir.uv.dx-pq#current | R5 | Section 2.2 - Reference Standard Substance |
| 13 | | Substance: Specimen Additive Substance | hl7.fhir.eu.laboratory#current | R4 | This profile defines how to represent Specimen Additive Substances in HL7 FHIR for the purpose of this guide. |
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D |
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D |
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| Substance.meta |
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| Substance.meta.profile |
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C |
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| Substance.implicitRules |
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| Substance.language |
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| Substance.text |
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| Substance.contained |
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| Substance.extension |
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S C D (3) |
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S C (2) |
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| Substance.extension.valueCodeableConcept |
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B M (2) |
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| Substance.modifierExtension |
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| Substance.identifier |
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| Substance.identifier.value |
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C D |
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| Substance.instance |
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| Substance.instance.quantity |
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| Substance.status |
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| Substance.category |
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| Substance.code |
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B M |
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B M |
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D B M |
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B M |
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B M |
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B M |
| Substance.code.coding |
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S C D (2) |
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| Substance.code.coding.display |
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C D |
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| Substance.code.coding.code |
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C D |
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| Substance.code.coding.system |
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C F D |
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| Substance.code.concept |
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| Substance.code.concept.coding |
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D |
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| Substance.description |
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| Substance.expiry |
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D |
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| Substance.quantity |
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| Substance.ingredient |
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| Substance.ingredient.extension |
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| Substance.ingredient.modifierExtension |
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| Substance.ingredient.quantity |
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| Substance.ingredient.substance[x] |
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B M |
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