CDC MME CQL Calculator
3.0.0 - release
This page is part of the CDC Opioid MME Calculator (v3.0.0: Release) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions
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<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Properties</b></p><table class="grid"><tr><td><b>Code</b></td><td><b>Type</b></td><td><b>Description</b></td></tr><tr><td>conversion-factor</td><td>decimal</td><td>Defines the conversion factor for a specific ingredient, when the conversion factor is the same for all dose forms and dose amounts for the ingredient. The value of this property will be the decimal representation of the conversion factor.</td></tr><tr><td>dose-form-conversion-factor</td><td>string</td><td>Defines the conversion factor for an ingredient when the conversion factor varies by the dose form of the medication. The value of this property will be a string of the form <dose-form-code>:<conversion-factor>[@<doses-per-day>], e.g. 970789:130, where '970789' is the RxNorm dose form code, and '130' is the decimal representation of the conversion factor. An example of a per-day conversion factor is fentanyl, 316987:7200@0.33333333, where 316987 is RxNorm dose form code, 7200 is the conversion factor, and 0.33333333 is the dosesPerDay, expressed as a decimal with a maximum of 8 digits after the decimal.</td></tr><tr><td>dose-range-conversion-factor</td><td>string</td><td>Defines the conversion factor for an ingredient when the conversion factor varies by the overall dose of the medication. The value of this property will be a string of the form <low-value>-<high-value>:<conversion-factor>, e.g. 1-20:4. Note that the low-value or high-value may be a wildcard '*' to indicate the range continues (e.g. '61-*:12' indicates the range is 61 or greater).</td></tr></table><p/><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>conversion-factor</b></td><td><b>dose-form-conversion-factor</b></td><td><b>dose-range-conversion-factor</b></td></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=2670">2670</a><a name="CDCMMEClinicalConversionFactors-2670"> </a></td><td>Codeine</td><td>0.15</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=4337">4337</a><a name="CDCMMEClinicalConversionFactors-4337"> </a></td><td>Fentanyl</td><td/><td>316987:7200@0.33333333</td><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=5489">5489</a><a name="CDCMMEClinicalConversionFactors-5489"> </a></td><td>Hydrocodone</td><td>1</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=3423">3423</a><a name="CDCMMEClinicalConversionFactors-3423"> </a></td><td>Hydromorphone</td><td>4</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=6813">6813</a><a name="CDCMMEClinicalConversionFactors-6813"> </a></td><td>Methadone</td><td/><td/><td>1-20:4, 21-40:8, 41-60:10, 61-*:12</td></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7052">7052</a><a name="CDCMMEClinicalConversionFactors-7052"> </a></td><td>Morphine</td><td>1</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7804">7804</a><a name="CDCMMEClinicalConversionFactors-7804"> </a></td><td>Oxycodone</td><td>1.5</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7814">7814</a><a name="CDCMMEClinicalConversionFactors-7814"> </a></td><td>Oxymorphone</td><td>3</td><td/><td/></tr></table></div>
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<valueString value="Floyd Eisenberg, MD, MPH"/>
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<valueString value="Kensaku Kawamoto, MD, PhD, MHS"/>
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<text value="Opioid Prescribing"/>
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<text value="Morphine Milligram Equivalent (MME)"/>
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value="NOTE: Do not use the calculated dose in MMEs to determine dosage for converting one opioid to another—the new opioid should be lower to avoid unintentional overdose caused by incomplete cross-tolerance and individual differences in opioid pharmacokinetics. Consult the medication label."/>
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value="Schadow G, McDonald CJ. The Unified Code for Units of Measure. Regenstrief Institute, Inc. and the UCUM Organization, 2017. Version 2.1, Revision 442. http://unitsofmeasure.org"/>
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<label value="Conversion Factors"/>
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<version value="3.0.0"/>
<name value="CDCMMEClinicalConversionFactors"/>
<title value="CDC MME Clinical Conversion Factors"/>
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<date value="2021-11-25T15:15:41+11:00"/>
<publisher value="Alphora"/>
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value="This Code System Supplement defines clinical conversion factors for calculating Morphine Milligram Equivalence (MME), as described in the CDC Opioid Prescribing Guideline. The supplement defines conversions factors for ingredients in one of 3 ways: 1, as a direct conversion factor for the ingredient, 2, as a dose-form-specific conversion factor for the ingredient, and 3, as a dose-quantity-ranged conversion factor for the ingredient. See the descriptions for each property for information on how the values are represented for the different conversion factors. For a given ingredient, only one of 'dose-form' or 'dose-range' will be present, with or without an ingredient-specific conversion factor. The properties together will enable a unique conversion factor to be determined if the input is within the expected range. If the input is outside the expected range, and there is no ingredient-specific conversion-factor specified, implementations should indicate a conversion factor could not be determined from the supplied information. All conversion factors supplied in this supplement are in 'mg/d'."/>
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<code value="conversion-factor"/>
<description
value="Defines the conversion factor for a specific ingredient, when the conversion factor is the same for all dose forms and dose amounts for the ingredient. The value of this property will be the decimal representation of the conversion factor."/>
<type value="decimal"/>
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<property>
<code value="dose-form-conversion-factor"/>
<description
value="Defines the conversion factor for an ingredient when the conversion factor varies by the dose form of the medication. The value of this property will be a string of the form <dose-form-code>:<conversion-factor>[@<doses-per-day>], e.g. 970789:130, where '970789' is the RxNorm dose form code, and '130' is the decimal representation of the conversion factor. An example of a per-day conversion factor is fentanyl, 316987:7200@0.33333333, where 316987 is RxNorm dose form code, 7200 is the conversion factor, and 0.33333333 is the dosesPerDay, expressed as a decimal with a maximum of 8 digits after the decimal."/>
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<property>
<code value="dose-range-conversion-factor"/>
<description
value="Defines the conversion factor for an ingredient when the conversion factor varies by the overall dose of the medication. The value of this property will be a string of the form <low-value>-<high-value>:<conversion-factor>, e.g. 1-20:4. Note that the low-value or high-value may be a wildcard '*' to indicate the range continues (e.g. '61-*:12' indicates the range is 61 or greater)."/>
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<display value="Codeine"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="0.15"/>
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<code value="4337"/>
<display value="Fentanyl"/>
<property>
<code value="dose-form-conversion-factor"/>
<valueString value="316987:7200@0.33333333"/>
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<concept>
<code value="5489"/>
<display value="Hydrocodone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="1"/>
</property>
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<concept>
<code value="3423"/>
<display value="Hydromorphone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="4"/>
</property>
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<concept>
<code value="6813"/>
<display value="Methadone"/>
<property>
<code value="dose-range-conversion-factor"/>
<valueString value="1-20:4"/>
</property>
<property>
<code value="dose-range-conversion-factor"/>
<valueString value="21-40:8"/>
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<property>
<code value="dose-range-conversion-factor"/>
<valueString value="41-60:10"/>
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<property>
<code value="dose-range-conversion-factor"/>
<valueString value="61-*:12"/>
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<code value="7052"/>
<display value="Morphine"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="1"/>
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<concept>
<code value="7804"/>
<display value="Oxycodone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="1.5"/>
</property>
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<concept>
<code value="7814"/>
<display value="Oxymorphone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="3"/>
</property>
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