CDC MME CQL Calculator
3.0.0 - release
CDC MME CQL Calculator
3.0.0 - release
This page is part of the CDC Opioid MME Calculator (v3.0.0: Release) based on FHIR R4. This is the current published version in its permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions 
<CodeSystem xmlns="http://hl7.org/fhir">
<id value="CDCMMEClinicalConversionFactors"/>
<meta>
<profile
value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-shareablecodesystem"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Properties</b></p><table class="grid"><tr><td><b>Code</b></td><td><b>Type</b></td><td><b>Description</b></td></tr><tr><td>conversion-factor</td><td>decimal</td><td>Defines the conversion factor for a specific ingredient, when the conversion factor is the same for all dose forms and dose amounts for the ingredient. The value of this property will be the decimal representation of the conversion factor.</td></tr><tr><td>dose-form-conversion-factor</td><td>string</td><td>Defines the conversion factor for an ingredient when the conversion factor varies by the dose form of the medication. The value of this property will be a string of the form <dose-form-code>:<conversion-factor>[@<doses-per-day>], e.g. 970789:130, where '970789' is the RxNorm dose form code, and '130' is the decimal representation of the conversion factor. An example of a per-day conversion factor is fentanyl, 316987:7200@0.33333333, where 316987 is RxNorm dose form code, 7200 is the conversion factor, and 0.33333333 is the dosesPerDay, expressed as a decimal with a maximum of 8 digits after the decimal.</td></tr><tr><td>dose-range-conversion-factor</td><td>string</td><td>Defines the conversion factor for an ingredient when the conversion factor varies by the overall dose of the medication. The value of this property will be a string of the form <low-value>-<high-value>:<conversion-factor>, e.g. 1-20:4. Note that the low-value or high-value may be a wildcard '*' to indicate the range continues (e.g. '61-*:12' indicates the range is 61 or greater).</td></tr></table><p/><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>conversion-factor</b></td><td><b>dose-form-conversion-factor</b></td><td><b>dose-range-conversion-factor</b></td></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=2670">2670</a><a name="CDCMMEClinicalConversionFactors-2670"> </a></td><td>Codeine</td><td>0.15</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=4337">4337</a><a name="CDCMMEClinicalConversionFactors-4337"> </a></td><td>Fentanyl</td><td/><td>316987:7200@0.33333333</td><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=5489">5489</a><a name="CDCMMEClinicalConversionFactors-5489"> </a></td><td>Hydrocodone</td><td>1</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=3423">3423</a><a name="CDCMMEClinicalConversionFactors-3423"> </a></td><td>Hydromorphone</td><td>4</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=6813">6813</a><a name="CDCMMEClinicalConversionFactors-6813"> </a></td><td>Methadone</td><td/><td/><td>1-20:4, 21-40:8, 41-60:10, 61-*:12</td></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7052">7052</a><a name="CDCMMEClinicalConversionFactors-7052"> </a></td><td>Morphine</td><td>1</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7804">7804</a><a name="CDCMMEClinicalConversionFactors-7804"> </a></td><td>Oxycodone</td><td>1.5</td><td/><td/></tr><tr><td><a style="white-space:nowrap" href="https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7814">7814</a><a name="CDCMMEClinicalConversionFactors-7814"> </a></td><td>Oxymorphone</td><td>3</td><td/><td/></tr></table></div>
</text>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
<valueCode value="shareable"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
<valueCode value="publishable"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel">
<valueCode value="structured"/>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/codesystem-sourceReference">
<valueUri
value="https://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf"/>
</extension>
<extension url="http://hl7.org/fhir/StructureDefinition/codesystem-author">
<valueString value="Floyd Eisenberg, MD, MPH"/>
</extension>
<extension url="http://hl7.org/fhir/StructureDefinition/codesystem-author">
<valueString value="Kensaku Kawamoto, MD, PhD, MHS"/>
</extension>
<extension url="http://hl7.org/fhir/StructureDefinition/codesystem-author">
<valueString value="Robert McClure, MD"/>
</extension>
<extension url="http://hl7.org/fhir/StructureDefinition/codesystem-author">
<valueString value="Bryn Rhodes"/>
</extension>
<extension url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-topic">
<valueCodeableConcept>
<text value="Opioid Prescribing"/>
</valueCodeableConcept>
</extension>
<extension url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-topic">
<valueCodeableConcept>
<text value="Morphine Milligram Equivalent (MME)"/>
</valueCodeableConcept>
</extension>
<extension url="http://hl7.org/fhir/StructureDefinition/codesystem-warning">
<valueMarkdown
value="NOTE: Do not use the calculated dose in MMEs to determine dosage for converting one opioid to another—the new opioid should be lower to avoid unintentional overdose caused by incomplete cross-tolerance and individual differences in opioid pharmacokinetics. Consult the medication label."/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-relatedArtifact">
<valueRelatedArtifact>
<type value="citation"/>
<label value="RxNORM"/>
<display
value="This product uses publicly available data courtesy of the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product."/>
<citation
value="Nelson SJ, Zeng K, Kilbourne J, Powell T, Moore R. Normalized names for clinical drugs: RxNorm at 6 years.<br/>J Am Med Inform Assoc. 2011 Jul-Aug;18(4)441-8. doi: 10.1136/amiajnl-2011-000116.<br/>Epub 2011 Apr 21. PubMed PMID: 21515544; PubMed Central PMCID: PMC3128404.<br/>[Full Text](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128404/)"/>
<url value="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128404/"/>
</valueRelatedArtifact>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-relatedArtifact">
<valueRelatedArtifact>
<type value="citation"/>
<label value="UCUM"/>
<display
value="This product includes all or a portion of the UCUM table, UCUM codes, and UCUM definitions or is derived from it, subject to a license from Regenstrief Institute, Inc. and The UCUM Organization. Your use of the UCUM table, UCUM codes, UCUM definitions also is subject to this license, a copy of which is available at http://unitsofmeasure.org<br/> The current complete UCUM table, UCUM Specification are available for download at http://unitsofmeasure.org<br/>The UCUM table and UCUM codes are copyright © 1995-2009, Regenstrief Institute, Inc. and the Unified Codes for Units of Measures (UCUM) Organization. All rights reserved."/>
<citation
value="Schadow G, McDonald CJ. The Unified Code for Units of Measure. Regenstrief Institute, Inc. and the UCUM Organization, 2017. Version 2.1, Revision 442. http://unitsofmeasure.org"/>
<url value="http://unitsofmeasure.org"/>
</valueRelatedArtifact>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-relatedArtifact">
<valueRelatedArtifact>
<type value="citation"/>
<label value="CDC Opioid Prescribing Guideline"/>
<display
value="Centers For Disease Control and Prevention (CDC) Guideline for Prescribing Opioids for Chronic Pain — United States, 2016"/>
<citation
value="Dowell D, Haegerich TM, Chou R. CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016. MMWR Recomm Rep 2016;65(No. RR-1):1–49. DOI: http://dx.doi.org/10.15585/mmwr.rr6501e1"/>
<url value="http://dx.doi.org/10.15585/mmwr.rr6501e1"/>
</valueRelatedArtifact>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-relatedArtifact">
<valueRelatedArtifact>
<type value="citation"/>
<label value="Calculating total daily dose of opioids for safer dosage"/>
<display
value="National Center for Injury Prevention and Control. Calculating total daily dose of opioids for safer dosage."/>
<citation
value="National Center for Injury Prevention and Control. Calculating total daily dose of opioids for safer dosage.<br/>Atlanta, GA: Centers for Disease Control and Prevention; https://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf, accessed November 19th, 2020"/>
<url
value="https://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf"/>
</valueRelatedArtifact>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-relatedArtifact">
<valueRelatedArtifact>
<type value="documentation"/>
<label value="Conversion Factors"/>
<display value="Conversion Factors"/>
<url
value="http://fhir.org/guides/cdc/opioid-mme-r4/conversion-factors.html"/>
</valueRelatedArtifact>
</extension>
<url
value="http://fhir.org/guides/cdc/opioid-mme-r4/CodeSystem/CDCMMEClinicalConversionFactors"/>
<version value="3.0.0"/>
<name value="CDCMMEClinicalConversionFactors"/>
<title value="CDC MME Clinical Conversion Factors"/>
<status value="active"/>
<experimental value="false"/>
<date value="2021-11-25T15:13:44+11:00"/>
<publisher value="Alphora"/>
<contact>
<telecom>
<system value="url"/>
<value value="http://alphora.com"/>
</telecom>
</contact>
<description
value="This Code System Supplement defines clinical conversion factors for calculating Morphine Milligram Equivalence (MME), as described in the CDC Opioid Prescribing Guideline. The supplement defines conversions factors for ingredients in one of 3 ways: 1, as a direct conversion factor for the ingredient, 2, as a dose-form-specific conversion factor for the ingredient, and 3, as a dose-quantity-ranged conversion factor for the ingredient. See the descriptions for each property for information on how the values are represented for the different conversion factors. For a given ingredient, only one of 'dose-form' or 'dose-range' will be present, with or without an ingredient-specific conversion factor. The properties together will enable a unique conversion factor to be determined if the input is within the expected range. If the input is outside the expected range, and there is no ingredient-specific conversion-factor specified, implementations should indicate a conversion factor could not be determined from the supplied information. All conversion factors supplied in this supplement are in 'mg/d'."/>
<useContext>
<code>
<system value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
<code value="focus"/>
<display value="Clinical Focus"/>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="182888003"/>
<display value="Medication requested (situation)"/>
</coding>
</valueCodeableConcept>
</useContext>
<useContext>
<code>
<system value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
<code value="focus"/>
<display value="Clinical Focus"/>
</code>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="82423001"/>
<display value="Chronic pain (finding)"/>
</coding>
</valueCodeableConcept>
</useContext>
<useContext>
<code>
<system value="http://terminology.hl7.org/CodeSystem/usage-context-type"/>
<code value="task"/>
<display value="Workflow Task"/>
</code>
<valueCodeableConcept>
<coding>
<system
value="http://fhir.org/guides/cdc/opioid-mme-r4/CodeSystem/CDCMMEUsageContextCodes"/>
<code value="mme-calculation"/>
<display value="MME Calculation"/>
</coding>
</valueCodeableConcept>
</useContext>
<jurisdiction>
<coding>
<system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
<code value="840"/>
</coding>
</jurisdiction>
<copyright
value="Copyright 2019+ Centers for Disease Control and Prevention (CDC)"/>
<content value="supplement"/>
<supplements value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<property>
<code value="conversion-factor"/>
<description
value="Defines the conversion factor for a specific ingredient, when the conversion factor is the same for all dose forms and dose amounts for the ingredient. The value of this property will be the decimal representation of the conversion factor."/>
<type value="decimal"/>
</property>
<property>
<code value="dose-form-conversion-factor"/>
<description
value="Defines the conversion factor for an ingredient when the conversion factor varies by the dose form of the medication. The value of this property will be a string of the form <dose-form-code>:<conversion-factor>[@<doses-per-day>], e.g. 970789:130, where '970789' is the RxNorm dose form code, and '130' is the decimal representation of the conversion factor. An example of a per-day conversion factor is fentanyl, 316987:7200@0.33333333, where 316987 is RxNorm dose form code, 7200 is the conversion factor, and 0.33333333 is the dosesPerDay, expressed as a decimal with a maximum of 8 digits after the decimal."/>
<type value="string"/>
</property>
<property>
<code value="dose-range-conversion-factor"/>
<description
value="Defines the conversion factor for an ingredient when the conversion factor varies by the overall dose of the medication. The value of this property will be a string of the form <low-value>-<high-value>:<conversion-factor>, e.g. 1-20:4. Note that the low-value or high-value may be a wildcard '*' to indicate the range continues (e.g. '61-*:12' indicates the range is 61 or greater)."/>
<type value="string"/>
</property>
<concept>
<code value="2670"/>
<display value="Codeine"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="0.15"/>
</property>
</concept>
<concept>
<code value="4337"/>
<display value="Fentanyl"/>
<property>
<code value="dose-form-conversion-factor"/>
<valueString value="316987:7200@0.33333333"/>
</property>
</concept>
<concept>
<code value="5489"/>
<display value="Hydrocodone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="1"/>
</property>
</concept>
<concept>
<code value="3423"/>
<display value="Hydromorphone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="4"/>
</property>
</concept>
<concept>
<code value="6813"/>
<display value="Methadone"/>
<property>
<code value="dose-range-conversion-factor"/>
<valueString value="1-20:4"/>
</property>
<property>
<code value="dose-range-conversion-factor"/>
<valueString value="21-40:8"/>
</property>
<property>
<code value="dose-range-conversion-factor"/>
<valueString value="41-60:10"/>
</property>
<property>
<code value="dose-range-conversion-factor"/>
<valueString value="61-*:12"/>
</property>
</concept>
<concept>
<code value="7052"/>
<display value="Morphine"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="1"/>
</property>
</concept>
<concept>
<code value="7804"/>
<display value="Oxycodone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="1.5"/>
</property>
</concept>
<concept>
<code value="7814"/>
<display value="Oxymorphone"/>
<property>
<code value="conversion-factor"/>
<valueDecimal value="3"/>
</property>
</concept>
</CodeSystem>
IG © 2019+ Alphora. Package fhir.cdc.opioid-mme-r4#3.0.0 based on FHIR 4.0.1. Generated 2021-11-25
Links: Table of Contents |
License |
QA Report
| Version History |